SPIRE2 spire type actin nucleation factor 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 84501)
Symbol: SPIRE2
Full name: spire type actin nucleation factor 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Also known as: Spir-2
Summary: Predicted to enable actin binding activity. Involved in establishment of meiotic spindle localization; formin-nucleated actin cable assembly; and positive regulation of double-strand break repair. Predicted to be located in cytoskeleton; cytosol; and plasma membrane. Predicted to be active in cell cortex and cytoplasmic vesicle membrane. Predicted to colocalize with cleavage furrow. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in stomach (RPKM 4.5), colon (RPKM 4.1) and 20 other tissues
Orthologs: mouse
Gene size: 42845bp
Exon count: 15