LAGE3 L antigen family member 3 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 8270)
Source: NCBI Gene (ID 8270)
Symbol: LAGE3
Full name: L antigen family member 3
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CVG5; DXS9879E; DXS9951E; ESO3; GAMOS2; ITBA2; Pcc1
Summary: This gene belongs to the ESO/LAGE gene family, members of which are clustered together on chromosome Xq28, and have similar exon-intron structures. Unlike the other family members which are normally expressed only in testis and activated in a wide range of human tumors, this gene is ubiquitously expressed in somatic tissues. The latter, combined with the finding that it is highly conserved in mouse and rat, suggests that the encoded protein is functionally important. An intronless pseudogene with high sequence similarity to this gene is located on chromosome 9. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in brain (RPKM 8.7), adrenal (RPKM 6.8) and 25 other tissues
Orthologs: mouse
Gene size: 1507bp
Exon count: 3