Full name: cubilin

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: IFCR; IGS; IGS1; MGA1; gp280

Summary: Cubilin (CUBN) acts as a receptor for intrinsic factor-vitamin B12 complexes. The role of receptor is supported by the presence of 27 CUB domains. Cubulin is located within the epithelium of intestine and kidney. Mutations in CUBN may play a role in autosomal recessive megaloblastic anemia. [provided by RefSeq, Jul 2008]

Expression: Biased expression in kidney (RPKM 65.4) and small intestine (RPKM 9.4)

Gene size: 305846bp

Exon count: 71