Rd3 retinal degeneration 3 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 74023)
Source: NCBI Gene (ID 74023)
Symbol: Rd3
Full name: retinal degeneration 3
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 3322402L07Rik; rd-3; rd3
Summary: Involved in negative regulation of guanylate cyclase activity and visual perception. Acts upstream of or within retina development in camera-type eye. Located in nucleus; photoreceptor inner segment; and photoreceptor outer segment. Is expressed in brain and sensory organ. Used to study Leber congenital amaurosis 12. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Leber congenital amaurosis 12; and retinal degeneration. Orthologous to human RD3 (RD3 regulator of GUCY2D). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in testis adult (RPKM 8.7) and lung adult (RPKM 1.0)
Orthologs: human
Gene size: 36924bp
Exon count: 5