Rnf146 ring finger protein 146 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 68031)
Source: NCBI Gene (ID 68031)
Symbol: Rnf146
Full name: ring finger protein 146
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 2610509H23Rik; Iduna
Summary: Predicted to enable poly-ADP-D-ribose binding activity and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including negative regulation of hydrogen peroxide-induced cell death; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to act upstream of or within Wnt signaling pathway. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in genitourinary system. Used to study cleidocranial dysplasia. Orthologous to human RNF146 (ring finger protein 146). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in bladder adult (RPKM 13.4), CNS E14 (RPKM 12.9) and 28 other tissues
Orthologs: human
Gene size: 18267bp
Exon count: 5