Full name: mitochondrial ribosomal protein L41

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: BMRP; MRP-L27; MRPL27; PIG3; RPML27

Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the YmL27 ribosomal protein family. [provided by RefSeq, Jul 2008]

Expression: Broad expression in fat (RPKM 57.1), colon (RPKM 44.9) and 24 other tissues

Gene size: 677bp

Exon count: 2