USP46 ubiquitin specific peptidase 46 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 64854)
Source: NCBI Gene (ID 64854)
Symbol: USP46
Full name: ubiquitin specific peptidase 46
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Homo sapiens
Summary: Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP46 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Jun 2009]
Expression: Ubiquitous expression in brain (RPKM 11.8), heart (RPKM 7.4) and 23 other tissues
Orthologs: mouse
Gene size: 68342bp
Exon count: 11