RPN1 ribophorin I [ Homo sapiens (human) ]
Source: NCBI Gene (ID 6184)
Source: NCBI Gene (ID 6184)
Symbol: RPN1
Full name: ribophorin I
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: OST1; RBPH1
Summary: This gene encodes a type I integral membrane protein found only in the rough endoplasmic reticulum. The encoded protein is part of an N-oligosaccharyl transferase complex that links high mannose oligosaccharides to asparagine residues found in the Asn-X-Ser/Thr consensus motif of nascent polypeptide chains. This protein forms part of the regulatory subunit of the 26S proteasome and may mediate binding of ubiquitin-like domains to this proteasome. [provided by RefSeq, Jul 2008]
Expression: Ubiquitous expression in thyroid (RPKM 116.8), placenta (RPKM 79.5) and 25 other tissues
Orthologs: mouse
Gene size: 30850bp
Exon count: 10