RENBP renin binding protein [ Homo sapiens (human) ]
Source: NCBI Gene (ID 5973)
Source: NCBI Gene (ID 5973)
Symbol: RENBP
Full name: renin binding protein
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: RBP; RNBP
Summary: The gene product inhibits renin activity by forming a dimer with renin, a complex known as high molecular weight renin. The encoded protein contains a leucine zipper domain, which is essential for its dimerization with renin. The gene product can catalyze the interconversion of N-acetylglucosamine to N-acetylmannosamine, indicating that it is a GlcNAc 2-epimerase. Transcript variants utilizing alternative promoters have been described in the literature. [provided by RefSeq, Jul 2008]
Expression: Broad expression in kidney (RPKM 29.7), spleen (RPKM 23.5) and 18 other tissues
Orthologs: mouse
Gene size: 9375bp
Exon count: 11