Full name: heterogeneous nuclear ribonucleoprotein U

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: DEE54; EIEE54; GRIP120; HNRNPU-AS1; HNRPU; SAF-A; SAFA; U21.1; hnRNP U; pp120

Summary: This gene encodes a member of a family of proteins that bind nucleic acids and function in the formation of ribonucleoprotein complexes in the nucleus with heterogeneous nuclear RNA (hnRNA). The encoded protein has affinity for both RNA and DNA, and binds scaffold-attached region (SAR) DNA. Mutations in this gene have been associated with epileptic encephalopathy, early infantile, 54. A pseudogene of this gene has been identified on chromosome 14. [provided by RefSeq, Jun 2017]

Expression: Ubiquitous expression in bone marrow (RPKM 31.0), lymph node (RPKM 28.0) and 25 other tissues

Gene size: 14247bp

Exon count: 14