GUCY1A2 guanylate cyclase 1 soluble subunit alpha 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 2977)
Symbol: GUCY1A2
Full name: guanylate cyclase 1 soluble subunit alpha 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: GC-SA2; GUC1A2
Summary: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Expression: Broad expression in endometrium (RPKM 8.8), placenta (RPKM 7.4) and 15 other tissues
Orthologs: mouse
Gene size: 344458bp
Exon count: 9