NDUFAF4 NADH:ubiquinone oxidoreductase complex assembly factor 4 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 29078)
Source: NCBI Gene (ID 29078)
Symbol: NDUFAF4
Full name: NADH:ubiquinone oxidoreductase complex assembly factor 4
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: C6orf66; HRPAP20; HSPC125; MC1DN15; My013; bA22L21.1
Summary: NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. [provided by RefSeq, Oct 2009]
Expression: Ubiquitous expression in heart (RPKM 11.9), brain (RPKM 11.8) and 25 other tissues
Orthologs: mouse
Gene size: 8577bp
Exon count: 3