Xrn2 5'-3' exoribonuclease 2 [ Mus musculus (house mouse) ] - Gene - Data resources

24128

Xrn2 5'-3' exoribonuclease 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 24128)

Symbol: Xrn2

Full name: 5'-3' exoribonuclease 2

Gene type: protein coding

RefSeq status: VALIDATED

Summary: Predicted to enable exoribonuclease activity, producing 5'-phosphomonoesters; identical protein binding activity; and nucleic acid binding activity. Involved in RNA metabolic process. Acts upstream of or within spermatogenesis. Predicted to be located in aggresome; nucleolus; and nucleoplasm. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in adenoid cystic carcinoma and lung cancer. Orthologous to human XRN2 (5'-3' exoribonuclease 2). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Ubiquitous expression in CNS E11.5 (RPKM 11.8), CNS E14 (RPKM 11.3) and 24 other tissues

Orthologs: human

Gene size: 65251bp

Exon count: 31