Full name: tyrosinase-related protein 1

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: Oca3; TRP-1; TRP1; Tyrp; b; brown; isa

Summary: Enables protein homodimerization activity. Involved in positive regulation of melanin biosynthetic process. Acts upstream of or within several processes, including acetoacetic acid metabolic process; melanocyte differentiation; and melanosome organization. Located in melanosome membrane. Is expressed in several structures, including hip; nervous system; sensory organ; skeleton; and skin. Human ortholog(s) of this gene implicated in oculocutaneous albinism; oculocutaneous albinism type III; and pigmentation disease. Orthologous to human TYRP1 (tyrosinase related protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Expression: Low expression observed in reference dataset

Gene size: 17614bp

Exon count: 8