Full name: thyrotropin releasing hormone

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Pro-TRH; Trf

Summary: This gene encodes a member of the thyrotropin-releasing hormone family. Cleavage of the encoded proprotein releases mature thyrotropin-releasing hormone, which is a tripeptide hypothalamic regulatory hormone. The mouse proprotein contains five thyrotropin-releasing hormone tripeptides. Thyrotropin-releasing hormone is involved in the regulation and release of thyroid-stimulating hormone, as well as prolactin. Disruption of this gene results in hypothyroidism, elevated thyroid-stimulating hormone levels, and hyperglycemia. [provided by RefSeq, Apr 2013]

Expression: Biased expression in frontal lobe adult (RPKM 13.0), testis adult (RPKM 2.3) and 5 other tissues

Gene size: 2590bp

Exon count: 3