Slc22a5 solute carrier family 22 (organic cation transporter), member 5 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 20520)
Source: NCBI Gene (ID 20520)
Symbol: Slc22a5
Full name: solute carrier family 22 (organic cation transporter), member 5
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Lstpl; Octn2; jvs
Summary: Enables (R)-carnitine transmembrane transporter activity. Involved in (R)-carnitine transmembrane transport and transport across blood-brain barrier. Acts upstream of or within several processes, including adult heart development; carnitine metabolic process; and carnitine transport. Located in brush border membrane. Is expressed in several structures, including liver; metanephros; nasal cavity mucosa; spleen; and testis. Used to study systemic primary carnitine deficiency disease. Human ortholog(s) of this gene implicated in Crohn's disease; cardiomyopathy; inherited metabolic disorder; and systemic primary carnitine deficiency disease. Orthologous to human SLC22A5 (solute carrier family 22 member 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in kidney adult (RPKM 72.8), placenta adult (RPKM 29.8) and 24 other tissues
Orthologs: human
Gene size: 27242bp
Exon count: 10