Full name: protein kinase, cAMP dependent regulatory, type I, alpha

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: 1300018C22Rik; RIalpha; Tse-1; Tse1

Summary: The encoded protein is a regulatory subunit of the cAMP-dependent protein kinase (PKA) complex, which is responsible for transducing most of the cAMP signals in eukaryotic cells. The inactive PKA complex contains two regulatory and two catalytic subunits. Binding of cAMP dissociates the complex, allowing monomeric catalytic subunits to phosphorylate cytosolic proteins or induce gene expression in the nucleus. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Sep 2015]

Expression: Ubiquitous expression in frontal lobe adult (RPKM 81.7), cerebellum adult (RPKM 81.5) and 28 other tissues

Gene size: 20641bp

Exon count: 15