Pde6b phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 18587)
Source: NCBI Gene (ID 18587)
Symbol: Pde6b
Full name: phosphodiesterase 6B, cGMP, rod receptor, beta polypeptide
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: Pdeb; r; rd; rd-1; rd1; rd10
Summary: Predicted to enable 3',5'-cyclic-nucleotide phosphodiesterase activity. Involved in entrainment of circadian clock by photoperiod. Acts upstream of or within detection of light stimulus and retina development in camera-type eye. Located in photoreceptor outer segment. Is expressed in esophagus; eye; and male reproductive gland or organ. Used to study congenital stationary night blindness autosomal dominant 2; retinitis pigmentosa; and retinitis pigmentosa 40. Human ortholog(s) of this gene implicated in congenital stationary night blindness autosomal dominant 2 and retinitis pigmentosa 40. Orthologous to human PDE6B (phosphodiesterase 6B). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset
Orthologs: human
Gene size: 43371bp
Exon count: 22