Full name: agouti related neuropeptide

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: AGRT; ART; ASIP2

Summary: This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation, and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity. [provided by RefSeq, Dec 2009]

Expression: Biased expression in adrenal (RPKM 1.6), lung (RPKM 0.8) and 5 other tissues

Gene size: 977bp

Exon count: 4