Full name: Meis homeobox 3

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: Mrg2

Summary: The protein encoding this gene belongs to the three amino acid loop extension family of homeodomain transcription factors, which play essential roles in many embryonic processes. These proteins are characterized by an atypical homeodomain containing a three amino acid loop extension between helices 1 and 2. Expression of this gene begins during the compaction stage of embryogenesis and continues into the blastocyst stage. This gene is also expressed in pancreatic islet cells and beta-cells and regulates beta-cell survival. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]

Expression: Broad expression in whole brain E14.5 (RPKM 38.1), CNS E14 (RPKM 35.8) and 21 other tissues

Gene size: 11752bp

Exon count: 15