Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 16511)
Source: NCBI Gene (ID 16511)
Symbol: Kcnh2
Full name: potassium voltage-gated channel, subfamily H (eag-related), member 2
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: ERG1; LQT; Lqt2; M-erg; Merg1; merg1a; merg1b
Summary: Enables inward rectifier potassium channel activity. Acts upstream of or within potassium ion transmembrane transport; regulation of heart rate by cardiac conduction; and regulation of ventricular cardiac muscle cell membrane repolarization. Located in cytoplasm; nuclear envelope; and plasma membrane. Is expressed in several structures, including brain; early conceptus; gonad; heart; and retina. Used to study short QT syndrome. Human ortholog(s) of this gene implicated in long QT syndrome; long QT syndrome 2; and short QT syndrome. Orthologous to human KCNH2 (potassium voltage-gated channel subfamily H member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in ovary adult (RPKM 33.4), thymus adult (RPKM 29.0) and 22 other tissues
Orthologs: human
Gene size: 32089bp
Exon count: 20