Eif6 eukaryotic translation initiation factor 6 [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 16418)
Symbol: Eif6
Full name: eukaryotic translation initiation factor 6
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Mus musculus
Also known as: 1110004P11; CAB; Itgb4bp; eIF-6; imc-415; p27(BBP); p27BBP
Summary: The protein encoded by this gene is a eukaryotic translation initiation factor that regulates both ribosome biogenesis and translation, which are rate-limiting factors for cell growth. The encoded protein binds 60S ribosomes and prevents their association with 40S ribosomes. This gene may play a role in oncogenesis as well. [provided by RefSeq, Aug 2015]
Expression: Ubiquitous expression in duodenum adult (RPKM 138.5), small intestine adult (RPKM 124.7) and 28 other tissues
Orthologs: human
Gene size: 7089bp
Exon count: 6