ACVR1C activin A receptor type 1C [ Homo sapiens (human) ] - Gene - Data resources

130399

ACVR1C activin A receptor type 1C [ Homo sapiens (human) ]
Source: NCBI Gene (ID 130399)

Symbol: ACVR1C

Full name: activin A receptor type 1C

Gene type: protein coding

RefSeq status: VALIDATED

Also known as: ACVRLK7; ALK7

Summary: ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).[supplied by OMIM, Mar 2008]

Expression: Biased expression in fat (RPKM 19.0), colon (RPKM 1.8) and 6 other tissues

Orthologs: mouse

Gene size: 102098bp

Exon count: 10