MAL2 mal, T cell differentiation protein 2 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 114569)
Symbol: MAL2
Full name: mal, T cell differentiation protein 2
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Summary: This gene encodes a multispan transmembrane protein belonging to the MAL proteolipid family. The protein is a component of lipid rafts and, in polarized cells, it primarily localizes to endosomal structures beneath the apical membrane. It is required for transcytosis, an intracellular transport pathway used to deliver membrane-bound proteins and exogenous cargos from the basolateral to the apical surface. [provided by RefSeq, Jul 2008]
Expression: Broad expression in esophagus (RPKM 140.3), thyroid (RPKM 100.0) and 16 other tissues
Orthologs: mouse
Gene size: 37311bp
Exon count: 4