Full name: chimerin 1

Gene type: protein coding

RefSeq status: REVIEWED

Also known as: ARHGAP2; CHN; DURS2; NC; RHOGAP2

Summary: This gene encodes GTPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. Mutations in this gene are associated with Duane's retraction syndrome 2 (DURS2). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]

Expression: Biased expression in brain (RPKM 113.6), placenta (RPKM 8.8) and 1 other tissue

Gene size: 206573bp

Exon count: 15