CCT7 chaperonin containing TCP1 subunit 7 [ Homo sapiens (human) ]
Source: NCBI Gene (ID 10574)
Source: NCBI Gene (ID 10574)
Symbol: CCT7
Full name: chaperonin containing TCP1 subunit 7
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Also known as: CCTETA; CCTH; NIP7-1; TCP1ETA
Summary: This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]
Expression: Ubiquitous expression in testis (RPKM 102.9), adrenal (RPKM 73.8) and 25 other tissues
Orthologs: mouse
Gene size: 18698bp
Exon count: 13