Pot1a protection of telomeres 1A [ Mus musculus (house mouse) ]
Source: NCBI Gene (ID 101185)
Source: NCBI Gene (ID 101185)
Symbol: Pot1a
Full name: protection of telomeres 1A
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Also known as: 1500031H18Rik; Pot1
Summary: Enables single-stranded telomeric DNA binding activity. Acts upstream of or within chromosome organization. Located in chromosome, telomeric region. Part of nuclear telomere cap complex. Is expressed in several structures, including basisphenoid bone; brain; genitourinary system; musculature; and otic capsule. Human ortholog(s) of this gene implicated in familial melanoma and high grade glioma. Orthologous to human POT1 (protection of telomeres 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in liver E14 (RPKM 7.1), liver E14.5 (RPKM 6.6) and 25 other tissues
Orthologs: human
Gene size: 65342bp
Exon count: 18