Scientific Name: Felis catus
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Feliformia-> Felidae
Summary: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_0028 | 2021.04 | 10X Genomics | Esophagus | Normal | 1928 | Link |
Vthunter_0029 | 2021.04 | 10X Genomics | Eyelid | Normal | 679 | Link |
Vthunter_0030 | 2021.04 | 10X Genomics | Heart | Normal | 8209 | Link |
Vthunter_0031 | 2021.04 | 10X Genomics | Kidney | Normal | 2831 | Link |
Vthunter_0032 | 2021.04 | 10X Genomics | Liver | Normal | 7889 | Link |
Vthunter_0033 | 2021.04 | 10X Genomics | Lung | Normal | 8591 | Link |
Vthunter_0034 | 2021.04 | 10X Genomics | Rectum | Normal | 1503 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in fat (RPKM 5.6), lymph node (RPKM 3.6) and 24 other tissues