Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 393
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 393
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 394
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 394
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Severity: Notice
Message: Trying to get property of non-object
Filename: controllers/VThunter.php
Line Number: 395
Backtrace:
File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 395
Function: _error_handler
File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once
Summary: This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_110082 | 2018.05 | Drop-seq | Pallium | Normal | 4187 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in skin (RPKM 17.4), testis (RPKM 9.9) and 25 other tissues
