VThunter

Drosophila

Scientific Name: Drosophila melanogaster

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Protostomia-> Ecdysozoa-> Panarthropoda-> Arthropoda-> Mandibulata-> Pancrustacea-> Hexapoda-> Insecta-> Dicondylia-> Pterygota-> Neoptera-> Endopterygota-> Diptera-> Brachycera-> Muscomorpha-> Eremoneura-> Cyclorrhapha-> Schizophora-> Acalyptratae-> Ephydroidea-> Drosophilidae-> Drosophilinae-> Drosophilini-> Drosophila-> Sophophora-> melanogaster group-> melanogaster subgroup

Influenza A virus

Family: Orthomyxoviridae

Receptor: UVRAG

Receptor UVRAG information

Summary: This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_1007	2017.12	Smart-seq2	Brain	Normal	1842	Link
Vthunter_1012	2018.09	Drop-seq	EyeDisc	Normal	6200	Link

mRNA expression of UVRAG in human tissues [NCBI]

Expression: Ubiquitous expression in fat (RPKM 5.6), lymph node (RPKM 3.6) and 24 other tissues