Scientific Name: Neovison vison
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Carnivora-> Caniformia-> Mustelidae-> Mustelinae-> Neovison
Summary: This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration and polymicrogyria (BLC-PMG), an autosomal recessive neurologic disorder that is also known as pseudo-TORCH syndrome. Alternative splicing results in multiple transcript variants. A related pseudogene is present 1.5 Mb downstream on the q arm of chromosome 5. [provided by RefSeq, Apr 2011] [NCBI] [Proteinatlas]
Data set information
| Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
|---|---|---|---|---|---|---|
| Vthunter_0019 | 2021.04 | 10X Genomics | Frontal | Normal | 4736 | Link |
| Vthunter_0020 | 2021.04 | 10X Genomics | Kidney | Normal | 9292 | Link |
| Vthunter_0021 | 2021.04 | 10X Genomics | Liver | Normal | 23084 | Link |
| Vthunter_0022 | 2021.04 | 10X Genomics | Lung | Normal | 2423 | Link |
Featureplot of receptors
Expression: Broad expression in thyroid (RPKM 16.6), lung (RPKM 10.9) and 18 other tissues
