VThunter
a database for single-cell screening of virus target cells in animal kingdom
...
Monk parakeet

Scientific Name: Myiopsitta monachus

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Sauropsida-> Sauria-> Archelosauria-> Archosauria-> Dinosauria-> Saurischia-> Theropoda-> Coelurosauria-> Aves-> Neognathae-> Psittaciformes-> Psittacidae-> Myiopsitta

...
Enterovirus A71

Family: Picornaviridae

Receptor: SELPLG

Receptor SELPLG information

Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011] [NCBI]  [Proteinatlas]

Data Source

Data set information

Project Date Technology Tissue Condition Cell PMID/DOI
Vthunter_0060 2021.04 iDrop PBMC Normal 1958 Link
Featureplot of receptors

Featureplot of receptors

mRNA expression of SELPLG in human tissues   [NCBI]

Expression: Broad expression in spleen (RPKM 29.0), lymph node (RPKM 26.4) and 22 other tissues

Protein expression of SELPLG in human tissues   [Proteinatlas]