VThunter

Pig

Scientific Name: Sus scrofa domestica

Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Deuterostomia-> Chordata-> Craniata-> Vertebrata-> Gnathostomata-> Teleostomi-> Euteleostomi-> Sarcopterygii-> Dipnotetrapodomorpha-> Tetrapoda-> Amniota-> Mammalia-> Theria-> Eutheria-> Boreoeutheria-> Laurasiatheria-> Artiodactyla-> Suina-> Suidae-> Sus-> Sus scrofa

Ebola virus

Family: Filoviridae

Receptor: NPC1

Receptor NPC1 information

Summary: This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009] [NCBI] [Proteinatlas]

Data Source

Data set information

Project	Date	Technology	Tissue	Condition	Cell	PMID/DOI
Vthunter_0046	2021.04	10X Genomics	Lung	Normal	21981	Link
Vthunter_0069	2021.04	10X Genomics	Frontal	Normal	8812	Link
Vthunter_0070	2021.04	10X Genomics	Occipital	Normal	6829	Link
Vthunter_0071	2021.04	10X Genomics	Parietal	Normal	6162	Link
Vthunter_0072	2021.04	10X Genomics	Hypothalamus	Normal	7302	Link
Vthunter_0073	2021.04	10X Genomics	Temporal	Normal	3145	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_0074	2021.04	iDrop	Lung	Normal	13580	Link
Vthunter_1013	2019.12	10X Genomics	Lung	Normal	7465	Link
Vthunter_1014	2019.12	10X Genomics	Lung	Normal	3987	Link