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Severity: Notice

Message: Trying to get property of non-object

Filename: controllers/VThunter.php

Line Number: 393

Backtrace:

File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 393
Function: _error_handler

File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Trying to get property of non-object

Filename: controllers/VThunter.php

Line Number: 394

Backtrace:

File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 394
Function: _error_handler

File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once

A PHP Error was encountered

Severity: Notice

Message: Trying to get property of non-object

Filename: controllers/VThunter.php

Line Number: 395

Backtrace:

File: /data/VThunterPlots/VThunter/application/controllers/VThunter.php
Line: 395
Function: _error_handler

File: /data/VThunterPlots/VThunter/index.php
Line: 315
Function: require_once

Summary: This gene encodes a large protein that resides in the limiting membrane of endosomes and lysosomes and mediates intracellular cholesterol trafficking via binding of cholesterol to its N-terminal domain. It is predicted to have a cytoplasmic C-terminus, 13 transmembrane domains, and 3 large loops in the lumen of the endosome - the last loop being at the N-terminus. This protein transports low-density lipoproteins to late endosomal/lysosomal compartments where they are hydrolized and released as free cholesterol. Defects in this gene cause Niemann-Pick type C disease, a rare autosomal recessive neurodegenerative disorder characterized by over accumulation of cholesterol and glycosphingolipids in late endosomal/lysosomal compartments.[provided by RefSeq, Aug 2009] [NCBI]  [Proteinatlas]

Data set information

Featureplot of receptors

Expression: Ubiquitous expression in adrenal (RPKM 13.9), brain (RPKM 10.0) and 24 other tissues?