Scientific Name: Drosophila melanogaster
Taxonomy: Cellular organisms-> Eukaryota-> Opisthokonta-> Metazoa-> Eumetazoa-> Bilateria-> Protostomia-> Ecdysozoa-> Panarthropoda-> Arthropoda-> Mandibulata-> Pancrustacea-> Hexapoda-> Insecta-> Dicondylia-> Pterygota-> Neoptera-> Endopterygota-> Diptera-> Brachycera-> Muscomorpha-> Eremoneura-> Cyclorrhapha-> Schizophora-> Acalyptratae-> Ephydroidea-> Drosophilidae-> Drosophilinae-> Drosophilini-> Drosophila-> Sophophora-> melanogaster group-> melanogaster subgroup
Summary: This gene is evolutionarily conserved, and its product is proposed to play a role in human cellular senescence and tumor suppression. Antiproliferative activity is reported to be localized to the 3' UTR, which is proposed to function as a trans-acting regulatory RNA. Several pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] [NCBI] [Proteinatlas]
Data set information
Project | Date | Technology | Tissue | Condition | Cell | PMID/DOI |
---|---|---|---|---|---|---|
Vthunter_1007 | 2017.12 | Smart-seq2 | Brain | Normal | 1842 | Link |
Vthunter_1012 | 2018.09 | Drop-seq | EyeDisc | Normal | 6200 | Link |
Featureplot of receptors
Expression: Ubiquitous expression in kidney (RPKM 68.3), colon (RPKM 44.2) and 25 other tissues